Solutions

Systematic preparation solutions around typical laboratory scenarios.

For NGS preparation, long-fragment DNA handling, chromatin shearing, and cell disruption, Boyibio connects equipment configuration, workflows, and resources.

Solution List

Application routes organized by experiment goal.

Each solution connects experiment purpose, sample type, process steps, and equipment features to support clearer preparation strategies.

NGS Preparation

MR300D Standardized NGS DNA Fragmentation Workflow

MR300D performs non-contact ultrasonic fragmentation for genomic DNA, cfDNA, plasmid DNA, and microbial DNA, covering mainstream NGS library fragment targets including 170 bp, 350 bp, 500 bp, and 800 bp.

A standardized DNA fragmentation, parameter, QC, and troubleshooting workflow for Illumina, MGI, and other NGS platforms based on the MR300D ultrasonic DNA shearing system.

· Random shearing without sequence bias
· 4℃ low-temperature control
· Concentrated and traceable fragment distribution

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ChIP Workflow

MR600D Standardized ChIP Chromatin Shearing Workflow

MR600D shears cross-linked chromatin through liquid-phase cavitation while preserving protein-DNA interactions, producing 200-1000 bp fragments for IP recovery, enrichment specificity, and sequencing library uniformity.

Uses the MR600D non-contact ultrasonic disruptor for gentle, uniform, and controlled shearing of cross-linked chromatin for ChIP, ChIP-qPCR, and ChIP-seq.

· Preserves protein-DNA cross-links
· Uniform energy across tubes
· Supports ChIP-seq and ChIP-qPCR

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Sample Processing

MR600D Standardized Cell Disruption Workflow

MR600D uses liquid-phase cavitation to generate uniform microjets and shear force, lysing adherent, suspension, primary, and stem cells while preserving protein activity, nucleic acid integrity, and active cellular components.

Uses the MR600D non-contact ultrasonic disruptor for gentle, uniform, and controlled cell lysis for protein, nucleic acid, enzyme activity, and related downstream assays.

· Non-contact and probe-free
· Low-temperature intermittent disruption
· Supports regular and sensitive cells

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