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Nucleic acid shearing system

MR300D DNA Shearing System (preview)

MR300D is designed for DNA fragmentation before NGS library preparation. It uses non-contact ultrasonic processing for multiple nucleic acid samples and focuses on fragment-size control, low-temperature handling, and batch repeatability for genomic DNA, cfDNA, plasmid DNA, and microbial DNA.

Product Overview

DNA shearing system for NGS sample preparation

MR300D is designed for DNA fragmentation before NGS library preparation. It uses non-contact ultrasonic processing for multiple nucleic acid samples and focuses on fragment-size control, low-temperature handling, and batch repeatability for genomic DNA, cfDNA, plasmid DNA, and microbial DNA.

Product Description

Product overview

MR300D is designed for DNA fragmentation before NGS library preparation. It uses non-contact ultrasonic processing for multiple nucleic acid samples and focuses on fragment-size control, low-temperature handling, and batch repeatability for genomic DNA, cfDNA, plasmid DNA, and microbial DNA.

Features

  • Non-contact processing reduces cross-contamination and probe-related contamination risk.
  • Supports parallel ultrasonic treatment of multiple tubes under low-temperature water circulation.
  • Adjustable amplitude, pulse timing, and total processing time help establish repeatable methods.
  • The tube rack rotates during sonication to improve energy distribution uniformity.
  • Suitable for DNA fragmentation, chromatin shearing, and cell or bacterial disruption workflows.
  • Tube racks can be customized for specific throughput and tube-format requirements.

Typical workflow

  1. Select the matching tube rack and verify water-circulation temperature.
  2. Load samples, remove bubbles, and place tubes in the ultrasonic chamber.
  3. Set amplitude, pulse timing, and total processing time.
  4. Run fragment, lysis, or downstream QC checks after processing.

Specifications

  • Source ID: 83
  • Published: 2026-05-15
  • Model: MR300D

Key Features

  • Non-contact processing reduces cross-contamination and probe-related contamination risk.
  • Supports parallel ultrasonic treatment of multiple tubes under low-temperature water circulation.
  • Adjustable amplitude, pulse timing, and total processing time help establish repeatable methods.
  • The tube rack rotates during sonication to improve energy distribution uniformity.
  • Suitable for DNA fragmentation, chromatin shearing, and cell or bacterial disruption workflows.
  • Tube racks can be customized for specific throughput and tube-format requirements.

Application Value

  • Improves consistency across multi-tube processing.
  • Reduces contamination risk from direct sample contact.
  • Supports method optimization, repeatability, and batch records.

Specifications

Source ID
83
Published
2026-05-15
Model
MR300D

Typical Workflow

  1. 01Select the matching tube rack and verify water-circulation temperature.
  2. 02Load samples, remove bubbles, and place tubes in the ultrasonic chamber.
  3. 03Set amplitude, pulse timing, and total processing time.
  4. 04Run fragment, lysis, or downstream QC checks after processing.